I constantly fiddle with this blog's look (I've probably gone through a few dozen templates, at least). But I think I've settled on a look that I'll be keeping for a while. Blogger tends to be regarded as the red-headed stepchild of blogging platforms, and I have considered jumping to Wordpress or Textpattern; but with some tweaking, you can actually make Blogger do some nice things.
First, perhaps most importantly, is the template: the built-in Blogger templates offer very little in the way of customization, and most of the third-party templates aren't much better -- and tend to be poorly designed and juvenile-looking, to boot. One big exception is Ourblogtemplates.com, which offers lots of professional-looking templates that can be customized in virtually every respect; the one I'm using, Newspaper, I like for being a simple, two-column, no-images design.
For specific inspiration, I looked to Wilson Miner's website, in particular the way he uses large font sizes to make things more readable, as well as the interplay he achieves between serif and sans-serif fonts. For the color scheme, I found this palette from a color website to be quite striking: blue tones and orange tones, of course, are complementary, and I've always liked the contrast between black (or nearly black), orange, and white. I think I also had in the back of my mind the cover to Penguin's Dictionary of Sociology:
Altogether, I'm pleased with how this blog looks now. Stability is seldom seen on the Internet, but I think this current design is a keeper.